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Modes of action of the archaeal Mre11/Rad50 DNA-repair complex revealed by fast-scan atomic force microscopy

Mre11 and Rad50 (M/R) proteins are part of an evolutionarily conserved macromolecular apparatus that maintains genomic integrity through repair pathways. Prior structural studies have revealed that this apparatus is extremely dynamic, displaying flexibility in the long coiled-coil regions of Rad50,...

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Detalles Bibliográficos
Autores principales: Zabolotnaya, Ekaterina, Mela, Ioanna, Williamson, Mark J., Bray, Sian M., Yau, Siu Kei, Papatziamou, Dimitra, Edwardson, J. Michael, Robinson, Nicholas P., Henderson, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334584/
https://www.ncbi.nlm.nih.gov/pubmed/32541055
http://dx.doi.org/10.1073/pnas.1915598117

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