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Modes of action of the archaeal Mre11/Rad50 DNA-repair complex revealed by fast-scan atomic force microscopy
Mre11 and Rad50 (M/R) proteins are part of an evolutionarily conserved macromolecular apparatus that maintains genomic integrity through repair pathways. Prior structural studies have revealed that this apparatus is extremely dynamic, displaying flexibility in the long coiled-coil regions of Rad50,...
Autores principales: | Zabolotnaya, Ekaterina, Mela, Ioanna, Williamson, Mark J., Bray, Sian M., Yau, Siu Kei, Papatziamou, Dimitra, Edwardson, J. Michael, Robinson, Nicholas P., Henderson, Robert M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334584/ https://www.ncbi.nlm.nih.gov/pubmed/32541055 http://dx.doi.org/10.1073/pnas.1915598117 |
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