Skp2 Depletion Reduces Tumor-Initiating Properties and Promotes Apoptosis in Synovial Sarcoma

Synovial sarcoma (SS) is an aggressive soft-tissue cancer with a poor prognosis and a propensity for local recurrence and distant metastasis. In this study, we investigated whether S phase kinase-associated protein (Skp2) plays an oncogenic role in tumor initiation, progression, and metastasis of SS...

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Detalles Bibliográficos
Autores principales: Wang, Jichuan, Sato, Kenji, O'Donnell, Ed, Singla, Amit, Yaguare, Simon, Aldahamsheh, Osama, Batko, Brian, Borjihan, Hasibagan, Tingling, Janet, Zhang, Jinghang, Weiser, Daniel A., Loeb, David M., Gorlick, Richard, Schwartz, Edward L., Yang, Rui, Zi, Xiaolin, Zhao, Hongling, Geller, David S., Hoang, Bang H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334610/
https://www.ncbi.nlm.nih.gov/pubmed/32623326
http://dx.doi.org/10.1016/j.tranon.2020.100809

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