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Fasting induces ANGPTL4 and reduces LPL activity in human adipose tissue
OBJECTIVE: Studies in mice have shown that the decrease in lipoprotein lipase (LPL) activity in adipose tissue upon fasting is mediated by induction of the inhibitor ANGPTL4. Here, we aimed to validate this concept in humans by determining the effect of a prolonged fast on ANGPTL4 and LPL gene and p...
Autores principales: | Ruppert, Philip M.M., Michielsen, Charlotte C.J.R., Hazebroek, Eric J., Pirayesh, Ali, Olivecrona, Gunilla, Afman, Lydia A., Kersten, Sander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334813/ https://www.ncbi.nlm.nih.gov/pubmed/32504883 http://dx.doi.org/10.1016/j.molmet.2020.101033 |
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