Low Utility of Repeat Real-Time PCR Testing for SARS-CoV-2 in Clinical Specimens

In a multicenter cohort of 22,315 patients tested for COVID-19, 1676 (7.5%) had repeat testing via real-time polymerase chain reaction following an initial negative test. Of those retested within 7 days of their first negative test, only 2.0% had a positive result. This suggests that repeat testing...

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Autores principales: Challener, Douglas W., Shah, Aditya, O’Horo, John C., Berbari, Elie, Binnicker, Matthew J., Tande, Aaron J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mayo Foundation for Medical Education and Research 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334934/
https://www.ncbi.nlm.nih.gov/pubmed/32861337
http://dx.doi.org/10.1016/j.mayocp.2020.06.020
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author Challener, Douglas W.
Shah, Aditya
O’Horo, John C.
Berbari, Elie
Binnicker, Matthew J.
Tande, Aaron J.
author_facet Challener, Douglas W.
Shah, Aditya
O’Horo, John C.
Berbari, Elie
Binnicker, Matthew J.
Tande, Aaron J.
author_sort Challener, Douglas W.
collection PubMed
description In a multicenter cohort of 22,315 patients tested for COVID-19, 1676 (7.5%) had repeat testing via real-time polymerase chain reaction following an initial negative test. Of those retested within 7 days of their first negative test, only 2.0% had a positive result. This suggests that repeat testing from the same source is unlikely to provide additional information.
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spelling pubmed-73349342020-07-06 Low Utility of Repeat Real-Time PCR Testing for SARS-CoV-2 in Clinical Specimens Challener, Douglas W. Shah, Aditya O’Horo, John C. Berbari, Elie Binnicker, Matthew J. Tande, Aaron J. Mayo Clin Proc Brief Report In a multicenter cohort of 22,315 patients tested for COVID-19, 1676 (7.5%) had repeat testing via real-time polymerase chain reaction following an initial negative test. Of those retested within 7 days of their first negative test, only 2.0% had a positive result. This suggests that repeat testing from the same source is unlikely to provide additional information. Mayo Foundation for Medical Education and Research 2020-09 2020-07-04 /pmc/articles/PMC7334934/ /pubmed/32861337 http://dx.doi.org/10.1016/j.mayocp.2020.06.020 Text en © 2020 Mayo Foundation for Medical Education and Research. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Brief Report
Challener, Douglas W.
Shah, Aditya
O’Horo, John C.
Berbari, Elie
Binnicker, Matthew J.
Tande, Aaron J.
Low Utility of Repeat Real-Time PCR Testing for SARS-CoV-2 in Clinical Specimens
title Low Utility of Repeat Real-Time PCR Testing for SARS-CoV-2 in Clinical Specimens
title_full Low Utility of Repeat Real-Time PCR Testing for SARS-CoV-2 in Clinical Specimens
title_fullStr Low Utility of Repeat Real-Time PCR Testing for SARS-CoV-2 in Clinical Specimens
title_full_unstemmed Low Utility of Repeat Real-Time PCR Testing for SARS-CoV-2 in Clinical Specimens
title_short Low Utility of Repeat Real-Time PCR Testing for SARS-CoV-2 in Clinical Specimens
title_sort low utility of repeat real-time pcr testing for sars-cov-2 in clinical specimens
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334934/
https://www.ncbi.nlm.nih.gov/pubmed/32861337
http://dx.doi.org/10.1016/j.mayocp.2020.06.020
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