Cargando…
Cadmium activates AMPA and NMDA receptors with M3 helix cysteine substitutions
AMPA and NMDA receptors are ligand-gated ion channels that depolarize postsynaptic neurons when activated by the neurotransmitter L-glutamate. Changes in the distribution and activity of these receptors underlie learning and memory, but excessive change is associated with an array of neurological di...
Autores principales: | Wilding, Timothy J., Huettner, James E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335009/ https://www.ncbi.nlm.nih.gov/pubmed/32342094 http://dx.doi.org/10.1085/jgp.201912537 |
Ejemplares similares
-
Cadmium opens GluK2 kainate receptors with cysteine substitutions at the M3 helix bundle crossing
por: Wilding, Timothy J., et al.
Publicado: (2019) -
Q/R site interactions with the M3 helix in GluK2 kainate receptor channels revealed by thermodynamic mutant cycles
por: Lopez, Melany N., et al.
Publicado: (2013) -
Amino Acid Substitutions in the Pore Helix of GluR6 Control Inhibition by Membrane Fatty Acids
por: Wilding, Timothy J., et al.
Publicado: (2008) -
Differential trafficking of AMPA receptors following activation of NMDA receptors and mGluRs
por: Sanderson, Thomas M, et al.
Publicado: (2011) -
The pre-M1 helix controls NMDA receptor gating
por: Short, Ben
Publicado: (2020)