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GL261 luciferase-expressing cells elicit an anti-tumor immune response: an evaluation of murine glioma models

Preclinical models that reliably recapitulate the immunosuppressive properties of human gliomas are essential to assess immune-based therapies. GL261 murine glioma cells are widely used as a syngeneic animal model of glioma, however, it has become common practice to transfect these cells with lucife...

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Detalles Bibliográficos
Autores principales: Sanchez, Victoria E., Lynes, John P., Walbridge, Stuart, Wang, Xiang, Edwards, Nancy A., Nwankwo, Anthony K., Sur, Hannah P., Dominah, Gifty A., Obungu, Arnold, Adamstein, Nicholas, Dagur, Pradeep K., Maric, Dragan, Munasinghe, Jeeva, Heiss, John D., Nduom, Edjah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335060/
https://www.ncbi.nlm.nih.gov/pubmed/32620877
http://dx.doi.org/10.1038/s41598-020-67411-w