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Subtyping analysis reveals new variants and accelerated evolution of Clostridioides difficile toxin B

Clostridioides difficile toxins (TcdA and TcdB) are major exotoxins responsible for C. difficile infection (CDI) associated diseases. The previously reported TcdB variants showed distinct biological features, immunoactivities, and potential pathogenicity in disease progression. Here, we performed gl...

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Detalles Bibliográficos
Autores principales: Shen, Enhui, Zhu, Kangli, Li, Danyang, Pan, Zhenrui, Luo, Yun, Bian, Qiao, He, Liuqing, Song, Xiaojun, Zhen, Ying, Jin, Dazhi, Tao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335066/
https://www.ncbi.nlm.nih.gov/pubmed/32620855
http://dx.doi.org/10.1038/s42003-020-1078-y