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Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders

Neurodevelopmental disorders have a heritable component and are associated with region specific alterations in brain anatomy. However, it is unclear how genetic risks for neurodevelopmental disorders are translated into spatially patterned brain vulnerabilities. Here, we integrated cortical neuroima...

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Detalles Bibliográficos
Autores principales: Seidlitz, Jakob, Nadig, Ajay, Liu, Siyuan, Bethlehem, Richard A. I., Vértes, Petra E., Morgan, Sarah E., Váša, František, Romero-Garcia, Rafael, Lalonde, François M., Clasen, Liv S., Blumenthal, Jonathan D., Paquola, Casey, Bernhardt, Boris, Wagstyl, Konrad, Polioudakis, Damon, de la Torre-Ubieta, Luis, Geschwind, Daniel H., Han, Joan C., Lee, Nancy R., Murphy, Declan G., Bullmore, Edward T., Raznahan, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335069/
https://www.ncbi.nlm.nih.gov/pubmed/32620757
http://dx.doi.org/10.1038/s41467-020-17051-5