Investigations of an inducible intact dystrophin gene excision system in cardiac and skeletal muscle in vivo

We sought here to induce the excision of a large intragenic segment within the intact dystrophin gene locus, with the ultimate goal to elucidate dystrophin protein function and stability in striated muscles in vivo. To this end, we implemented an inducible-gene excision methodology using a floxed al...

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Detalles Bibliográficos
Autores principales: Bez Batti Angulski, Addeli, Bauer, John, Cohen, Houda, Kobuke, Kazuhiro, Campbell, Kevin P., Metzger, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335168/
https://www.ncbi.nlm.nih.gov/pubmed/32620803
http://dx.doi.org/10.1038/s41598-020-67372-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335168/
https://www.ncbi.nlm.nih.gov/pubmed/32620803
http://dx.doi.org/10.1038/s41598-020-67372-0

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