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Investigations of an inducible intact dystrophin gene excision system in cardiac and skeletal muscle in vivo
We sought here to induce the excision of a large intragenic segment within the intact dystrophin gene locus, with the ultimate goal to elucidate dystrophin protein function and stability in striated muscles in vivo. To this end, we implemented an inducible-gene excision methodology using a floxed al...
Autores principales: | Bez Batti Angulski, Addeli, Bauer, John, Cohen, Houda, Kobuke, Kazuhiro, Campbell, Kevin P., Metzger, Joseph M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335168/ https://www.ncbi.nlm.nih.gov/pubmed/32620803 http://dx.doi.org/10.1038/s41598-020-67372-0 |
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