Development of fluorescence oligonucleotide probes based on cytosine- and guanine-rich sequences

The properties of cytosine- and guanine-rich oligonucleotides contributed to employing them as sensing elements in various biosensors. In this paper, we report our current development of fluorescence oligonucleotide probes based on i-motif or G-quadruplex forming oligonucleotides for cellular measur...

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Autores principales: Dembska, Anna, Świtalska, Angelika, Fedoruk-Wyszomirska, Agnieszka, Juskowiak, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335195/
https://www.ncbi.nlm.nih.gov/pubmed/32620895
http://dx.doi.org/10.1038/s41598-020-67745-5
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author Dembska, Anna
Świtalska, Angelika
Fedoruk-Wyszomirska, Agnieszka
Juskowiak, Bernard
author_facet Dembska, Anna
Świtalska, Angelika
Fedoruk-Wyszomirska, Agnieszka
Juskowiak, Bernard
author_sort Dembska, Anna
collection PubMed
description The properties of cytosine- and guanine-rich oligonucleotides contributed to employing them as sensing elements in various biosensors. In this paper, we report our current development of fluorescence oligonucleotide probes based on i-motif or G-quadruplex forming oligonucleotides for cellular measurements or bioimaging applications. Additionally, we also focus on the spectral properties of the new fluorescent silver nanoclusters based system (ChONC12-AgNCs) that is able to anchor at the Langmuir monolayer interface, which is mimicking the surface of living cells membrane.
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spelling pubmed-73351952020-07-07 Development of fluorescence oligonucleotide probes based on cytosine- and guanine-rich sequences Dembska, Anna Świtalska, Angelika Fedoruk-Wyszomirska, Agnieszka Juskowiak, Bernard Sci Rep Article The properties of cytosine- and guanine-rich oligonucleotides contributed to employing them as sensing elements in various biosensors. In this paper, we report our current development of fluorescence oligonucleotide probes based on i-motif or G-quadruplex forming oligonucleotides for cellular measurements or bioimaging applications. Additionally, we also focus on the spectral properties of the new fluorescent silver nanoclusters based system (ChONC12-AgNCs) that is able to anchor at the Langmuir monolayer interface, which is mimicking the surface of living cells membrane. Nature Publishing Group UK 2020-07-03 /pmc/articles/PMC7335195/ /pubmed/32620895 http://dx.doi.org/10.1038/s41598-020-67745-5 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Dembska, Anna
Świtalska, Angelika
Fedoruk-Wyszomirska, Agnieszka
Juskowiak, Bernard
Development of fluorescence oligonucleotide probes based on cytosine- and guanine-rich sequences
title Development of fluorescence oligonucleotide probes based on cytosine- and guanine-rich sequences
title_full Development of fluorescence oligonucleotide probes based on cytosine- and guanine-rich sequences
title_fullStr Development of fluorescence oligonucleotide probes based on cytosine- and guanine-rich sequences
title_full_unstemmed Development of fluorescence oligonucleotide probes based on cytosine- and guanine-rich sequences
title_short Development of fluorescence oligonucleotide probes based on cytosine- and guanine-rich sequences
title_sort development of fluorescence oligonucleotide probes based on cytosine- and guanine-rich sequences
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335195/
https://www.ncbi.nlm.nih.gov/pubmed/32620895
http://dx.doi.org/10.1038/s41598-020-67745-5
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