Cargando…

Recent insights for the emerging COVID-19: Drug discovery, therapeutic options and vaccine development

SARS-CoV-2 has been marked as a highly pathogenic coronavirus of COVID-19 disease into the human population, causing over 5.5 million confirmed cases worldwide. As COVID-19 has posed a global threat with significant human casualties and severe economic losses, there is a pressing demand to further u...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Yuefei, Li, Jia, Pang, Zhiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335243/
https://www.ncbi.nlm.nih.gov/pubmed/32837565
http://dx.doi.org/10.1016/j.ajps.2020.06.001
_version_ 1783554103748591616
author Zhu, Yuefei
Li, Jia
Pang, Zhiqing
author_facet Zhu, Yuefei
Li, Jia
Pang, Zhiqing
author_sort Zhu, Yuefei
collection PubMed
description SARS-CoV-2 has been marked as a highly pathogenic coronavirus of COVID-19 disease into the human population, causing over 5.5 million confirmed cases worldwide. As COVID-19 has posed a global threat with significant human casualties and severe economic losses, there is a pressing demand to further understand the current situation and develop rational strategies to contain the drastic spread of the virus. Although there are no specific antiviral therapies that have proven effective in randomized clinical trials, currently, the rapid detection technology along with several promising therapeutics for COVID-19 have mitigated its drastic transmission. Besides, global institutions and corporations have commenced to parse out effective vaccines for the prevention of COVID-19. Herein, the present review will give exhaustive details of extensive researches concerning the drug discovery and therapeutic options for COVID-19 as well as some insightful discussions of the status of COVID-19.
format Online
Article
Text
id pubmed-7335243
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Shenyang Pharmaceutical University
record_format MEDLINE/PubMed
spelling pubmed-73352432020-07-06 Recent insights for the emerging COVID-19: Drug discovery, therapeutic options and vaccine development Zhu, Yuefei Li, Jia Pang, Zhiqing Asian J Pharm Sci Review SARS-CoV-2 has been marked as a highly pathogenic coronavirus of COVID-19 disease into the human population, causing over 5.5 million confirmed cases worldwide. As COVID-19 has posed a global threat with significant human casualties and severe economic losses, there is a pressing demand to further understand the current situation and develop rational strategies to contain the drastic spread of the virus. Although there are no specific antiviral therapies that have proven effective in randomized clinical trials, currently, the rapid detection technology along with several promising therapeutics for COVID-19 have mitigated its drastic transmission. Besides, global institutions and corporations have commenced to parse out effective vaccines for the prevention of COVID-19. Herein, the present review will give exhaustive details of extensive researches concerning the drug discovery and therapeutic options for COVID-19 as well as some insightful discussions of the status of COVID-19. Shenyang Pharmaceutical University 2021-01 2020-07-04 /pmc/articles/PMC7335243/ /pubmed/32837565 http://dx.doi.org/10.1016/j.ajps.2020.06.001 Text en © 2020 Shenyang Pharmaceutical University. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Zhu, Yuefei
Li, Jia
Pang, Zhiqing
Recent insights for the emerging COVID-19: Drug discovery, therapeutic options and vaccine development
title Recent insights for the emerging COVID-19: Drug discovery, therapeutic options and vaccine development
title_full Recent insights for the emerging COVID-19: Drug discovery, therapeutic options and vaccine development
title_fullStr Recent insights for the emerging COVID-19: Drug discovery, therapeutic options and vaccine development
title_full_unstemmed Recent insights for the emerging COVID-19: Drug discovery, therapeutic options and vaccine development
title_short Recent insights for the emerging COVID-19: Drug discovery, therapeutic options and vaccine development
title_sort recent insights for the emerging covid-19: drug discovery, therapeutic options and vaccine development
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335243/
https://www.ncbi.nlm.nih.gov/pubmed/32837565
http://dx.doi.org/10.1016/j.ajps.2020.06.001
work_keys_str_mv AT zhuyuefei recentinsightsfortheemergingcovid19drugdiscoverytherapeuticoptionsandvaccinedevelopment
AT lijia recentinsightsfortheemergingcovid19drugdiscoverytherapeuticoptionsandvaccinedevelopment
AT pangzhiqing recentinsightsfortheemergingcovid19drugdiscoverytherapeuticoptionsandvaccinedevelopment