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XEN(®) Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma

The XEN Gel Microstent is a subconjunctival microinvasive glaucoma surgical device developed with the aim of improving the predictability and safety profile of bleb-forming glaucoma surgical procedures. The stent is a hydrophilic tube composed of a porcine gel cross-linked with glutaraldehyde with g...

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Autores principales: Fea, Antonio M, Durr, Georges M, Marolo, Paola, Malinverni, Lorenza, Economou, Mario A, Ahmed, Ike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335291/
https://www.ncbi.nlm.nih.gov/pubmed/32636610
http://dx.doi.org/10.2147/OPTH.S178348
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author Fea, Antonio M
Durr, Georges M
Marolo, Paola
Malinverni, Lorenza
Economou, Mario A
Ahmed, Ike
author_facet Fea, Antonio M
Durr, Georges M
Marolo, Paola
Malinverni, Lorenza
Economou, Mario A
Ahmed, Ike
author_sort Fea, Antonio M
collection PubMed
description The XEN Gel Microstent is a subconjunctival microinvasive glaucoma surgical device developed with the aim of improving the predictability and safety profile of bleb-forming glaucoma surgical procedures. The stent is a hydrophilic tube composed of a porcine gel cross-linked with glutaraldehyde with good stability and biocompatibility with minimal tissue reaction. This device has demonstrated promising outcomes with fewer risks compared to traditional surgeries. The aim of the review is to present early studies on different designs of the XEN Gel Stent, to summarize different surgical techniques of implantation and to analyze more comprehensively the results, complications and rates of needling of the commercially available device (Xen 45). The review will address separately special cases (PXG, UVG, ICE, congenital glaucoma) and describe small series and case reports.
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spelling pubmed-73352912020-07-06 XEN(®) Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma Fea, Antonio M Durr, Georges M Marolo, Paola Malinverni, Lorenza Economou, Mario A Ahmed, Ike Clin Ophthalmol Review The XEN Gel Microstent is a subconjunctival microinvasive glaucoma surgical device developed with the aim of improving the predictability and safety profile of bleb-forming glaucoma surgical procedures. The stent is a hydrophilic tube composed of a porcine gel cross-linked with glutaraldehyde with good stability and biocompatibility with minimal tissue reaction. This device has demonstrated promising outcomes with fewer risks compared to traditional surgeries. The aim of the review is to present early studies on different designs of the XEN Gel Stent, to summarize different surgical techniques of implantation and to analyze more comprehensively the results, complications and rates of needling of the commercially available device (Xen 45). The review will address separately special cases (PXG, UVG, ICE, congenital glaucoma) and describe small series and case reports. Dove 2020-06-30 /pmc/articles/PMC7335291/ /pubmed/32636610 http://dx.doi.org/10.2147/OPTH.S178348 Text en © 2020 Fea et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Fea, Antonio M
Durr, Georges M
Marolo, Paola
Malinverni, Lorenza
Economou, Mario A
Ahmed, Ike
XEN(®) Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma
title XEN(®) Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma
title_full XEN(®) Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma
title_fullStr XEN(®) Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma
title_full_unstemmed XEN(®) Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma
title_short XEN(®) Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma
title_sort xen(®) gel stent: a comprehensive review on its use as a treatment option for refractory glaucoma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335291/
https://www.ncbi.nlm.nih.gov/pubmed/32636610
http://dx.doi.org/10.2147/OPTH.S178348
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