Human Condensin I and II Drive Extensive ATP-Dependent Compaction of Nucleosome-Bound DNA

Structural maintenance of chromosomes (SMC) complexes are essential for genome organization from bacteria to humans, but their mechanisms of action remain poorly understood. Here, we characterize human SMC complexes condensin I and II and unveil the architecture of the human condensin II complex, re...

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Detalles Bibliográficos
Autores principales: Kong, Muwen, Cutts, Erin E., Pan, Dongqing, Beuron, Fabienne, Kaliyappan, Thangavelu, Xue, Chaoyou, Morris, Edward P., Musacchio, Andrea, Vannini, Alessandro, Greene, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335352/
https://www.ncbi.nlm.nih.gov/pubmed/32445620
http://dx.doi.org/10.1016/j.molcel.2020.04.026

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