The First Asian, Single-Center Experience of Blastocyst Preimplantation Genetic Diagnosis with HLA Matching in Thailand for the Prevention of Thalassemia and Subsequent Curative Hematopoietic Stem Cell Transplantation of Twelve Affected Siblings

RESULTS: In 221 cycles from 138 patients (104 cycles requiring HLA matching), 90.5% had embryo(s) biopsied for genetic testing. There were 119 embryo transfers for thalassemia (76) and thalassemia-HLA cases (43), respectively, resulting in overall clinical pregnancy rates of 54.6%, implantation rate...

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Detalles Bibliográficos
Autores principales: Tiewsiri, Kasorn, Manipalviratn, Somjate, Sutheesophon, Warachaya, Vanichsetakul, Preeda, Thaijaroen, Piyarat, Ketcharoon, Pagawadee, Bradley, Cara K., McArthur, Steven J., Krutsawad, Weena, Marshall, James T. A., Papadopoulos, Konstantinos I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335404/
https://www.ncbi.nlm.nih.gov/pubmed/32685500
http://dx.doi.org/10.1155/2020/5292090

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