Cargando…

Modulating effect of vitamin D3 on the mutagenicity and carcinogenicity of doxorubicin in Drosophila melanogaster and in silico studies

Vitamin D3 (VD3) deficiency increases DNA damage, while supplementation may exert a pro-oxidant activity, prevent viral infections and formation of tumors. The aim of this study was to investigate the mutagenicity and carcinogenicity of VD3 alone or in combination with doxorubicin (DXR) using the So...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vasconcelos, Mirley Alves, Orsolin, Priscila Capelari, Oliveira, Victor Constante, Lima, Paula Marynella Alves Pereira, Naves, Maria Paula Carvalho, de Morais, Cássio Resende, Nicolau-Júnior, Nilson, Bonetti, Ana Maria, Spanó, Mário Antônio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335493/ https://www.ncbi.nlm.nih.gov/pubmed/32640329 http://dx.doi.org/10.1016/j.fct.2020.111549

Ejemplares similares

Mutagens and Carcinogens in the Diet
por: Kaplan, Daniel Lee
Publicado: (1991)

Carcinogenicity of food mutagens.
por: Sugimura, T, et al.
Publicado: (1996)

Carcinogens are mutagens: their detection and classification.
por: Ames, B N
Publicado: (1973)

Molecular Biology of Mutagens and Carcinogens
por: Fox, M.
Publicado: (1984)

Potential Industrial Carcinogens and Mutagens
por: Purchase, I. F. H.
Publicado: (1979)

Mechanisms of vinyl chloride carcinogenicity/mutagenicity.
por: Hathaway, D. E.
Publicado: (1981)

Carcinogenic, teratogenic, and mutagenic effects of arsenic.
por: Bencko, V
Publicado: (1977)

Chemistry of mutagens and carcinogens in broiled food.
por: Nishimura, S
Publicado: (1986)

Mutagenic carcinogens and noncarcinogens in transgenic mice.
por: Günzel, P, et al.
Publicado: (1997)

Mutagenic/carcinogenic potential of DEHP and MEHP.
por: Tomita, I, et al.
Publicado: (1982)

Advantages of and problems with short-term mutagenicity tests for the assessment of mutagenic and carcinogenic risk.
por: Ramel, C
Publicado: (1983)

Naturally Occurring Carcinogens, Mutagens and Modulators of Carcinogenesis
por: Fox, M.
Publicado: (1980)

Mutagenic and carcinogenic properties of polycyclic aromatic hydrocarbons.
por: Pashin, Y V, et al.
Publicado: (1979)

Mutagenic and carcinogenic risks associated with halogenated olefins.
por: Infante, P F
Publicado: (1977)

Thresholds in toxic, teratogenic, mutagenic, and carcinogenic effects.
por: Freese, E
Publicado: (1973)

The use of bacterial mutagenicity tests in carcinogenicity studies.
por: Venitt, S.
Publicado: (1980)

Lack of initiating activity in mutagens which are not carcinogenic.
por: Coombs, M. M., et al.
Publicado: (1978)

N-hydroxylation of carcinogenic and mutagenic aromatic amines.
por: Kato, R, et al.
Publicado: (1983)

Genetic and Epigenetic Effects of Environmental Mutagens and Carcinogens
por: Pulliero, Alessandra, et al.
Publicado: (2015)

Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals
por: Dasharathy, Sukeerthi, et al.
Publicado: (2022)

Distinction of mutagenic carcinogens from a mutagenic noncarcinogen in the big blue transgenic mouse.
por: Cunningham, M L, et al.
Publicado: (1996)

A selective Cu(II) complex with 4-fluorophenoxyacetic acid hydrazide and phenanthroline displays DNA-cleaving and pro-apoptotic properties in cancer cells
por: Machado, Pedro Henrique Alves, et al.
Publicado: (2021)

The nature of the mutagenicity and carcinogenicity of nitrated, aromatic compounds in the environment.
por: Tokiwa, H, et al.
Publicado: (1987)

Proceedings: Carcinogenic and mutagenic activity of chromium containing materials.
por: Levy, L. S., et al.
Publicado: (1975)

Identification and evaluation of potentially mutagenic and carcinogenic food contaminants
por: Rasinger, Josef D, et al.
Publicado: (2018)

International Commission for Protection against Environmental Mutagens and Carcinogens (ICPEMC)
por: Lohman, P. H. M.
Publicado: (1979)

Mechanistic relationship among mutagenicity, skin sensitization, and skin carcinogenicity.
por: Ashby, J, et al.
Publicado: (1993)

Current cytogenetic methods for detecting exposure and effects of mutagens and carcinogens.
por: Natarajan, A T, et al.
Publicado: (1996)

Proceedings: Mutagenicity of hair colourants in bacteria: possible link with carcinogenicity.
por: Venitt, S., et al.
Publicado: (1975)

Structure-activity relations: maximizing the usefulness of mutagenicity and carcinogenicity databases.
por: Klopman, G, et al.
Publicado: (1991)

Role of Mutagenicity in Asbestos Fiber-Induced Carcinogenicity and Other Diseases
por: Huang, Sarah X. L., et al.
Publicado: (2011)

QSAR ligand dataset for modelling mutagenicity, genotoxicity, and rodent carcinogenicity
por: Guan, Davy, et al.
Publicado: (2018)

Copper(II) Complex Containing 4-Fluorophenoxyacetic Acid Hydrazide and 1,10-Phenanthroline: A Prostate Cancer Cell-Selective and Low-Toxic Copper(II) Compound
por: Bontempo, Nayara Júnia de Souza, et al.
Publicado: (2022)

Enzymatic Hydrolysis of Rutin: Evaluation of Kinetic Parameters and Anti-Proliferative, Mutagenic and Anti-Mutagenic Effects
por: Sobreiro, Mariana Alves, et al.
Publicado: (2023)

Formation and fate of gaseous and particulate mutagens and carcinogens in real and simulated atmospheres.
por: Pitts, J N
Publicado: (1983)

Comparison between carcinogenicity and mutagenicity based on chemicals evaluated in the IARC monographs.
por: Bartsch, H, et al.
Publicado: (1983)

Evaluation of the mutagenicity and carcinogenicity of motor vehicle emissions in short-term bioassays.
por: Lewtas, J
Publicado: (1983)

Consensus report: mutagenicity and carcinogenicity of car exhausts and coal combustion emissions.
Publicado: (1983)

Computational insights into the mutagenicity of two tobacco-derived carcinogenic DNA lesions
por: Wilson, Katie A, et al.
Publicado: (2018)

MicotoXilico: An Interactive Database to Predict Mutagenicity, Genotoxicity, and Carcinogenicity of Mycotoxins
por: Tolosa, Josefa, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_aethtvo3d3kmn8b8hvia5qu0tj