IQGAP1 control of centrosome function defines distinct variants of triple negative breast cancer

Triple negative breast cancer (TNBC) is a heterogenous and lethal disease that lacks diagnostic markers and therapeutic targets; as such common targets are highly sought after. IQGAP1 is a signaling scaffold implicated in TNBC, but its mechanism is unknown. Here we show that IQGAP1 localizes to the...

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Detalles Bibliográficos
Autores principales: Osman, Mahasin A., Antonisamy, William James, Yakirevich, Evgeny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335670/
https://www.ncbi.nlm.nih.gov/pubmed/32655836
http://dx.doi.org/10.18632/oncotarget.27623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335670/
https://www.ncbi.nlm.nih.gov/pubmed/32655836
http://dx.doi.org/10.18632/oncotarget.27623

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