Cargando…

Thymol Isolated from Thymus vulgaris L. Inhibits Colorectal Cancer Cell Growth and Metastasis by Suppressing the Wnt/β-Catenin Pathway

PURPOSE: Colorectal cancer (CRC) is one of the most commonly occurring cancers and is associated with high morbidity and mortality. Nevertheless, there is currently no safe and effective treatment for this condition. Thymol is a phenolic compound that is recognized as safe for use in food as well as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zeng, Qiongyao, Che, Yuncheng, Zhang, Yu, Chen, Mei, Guo, Qiang, Zhang, Wenjing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335897/ https://www.ncbi.nlm.nih.gov/pubmed/32669835 http://dx.doi.org/10.2147/DDDT.S254218

Ejemplares similares

Effects of Thymol and Carvacrol, Constituents of Thymus vulgaris L. Essential Oil, on the Inflammatory Response
por: Fachini-Queiroz, Fernanda Carolina, et al.
Publicado: (2012)

Effect of Thymus vulgaris L. essential oil and thymol on the microbiological properties of meat and meat products: A review
por: Posgay, Miklós, et al.
Publicado: (2022)

A validated high performance liquid chromatography method for the analysis of thymol and carvacrol in Thymus vulgaris L. volatile oil
por: Hajimehdipoor, H., et al.
Publicado: (2010)

Baicalein suppresses the proliferation and invasiveness of colorectal cancer cells by inhibiting Snail-induced epithelial-mesenchymal transition
por: Zeng, Qiongyao, et al.
Publicado: (2020)

The effect of induced polyploidy on phytochemistry, cellular organelles and the expression of genes involved in thymol and carvacrol biosynthetic pathway in thyme (Thymus vulgaris)
por: Mohammadi, Valiollah, et al.
Publicado: (2023)

Sanguinarine suppresses migration and metastasis in colorectal carcinoma associated with the inversion of EMT through the Wnt/β‐catenin signaling
por: Zhu, Man, et al.
Publicado: (2020)

Insecticidal toxicities of carvacrol and thymol derived from Thymus vulgaris Lin. against Pochazia shantungensis Chou & Lu., newly recorded pest
por: Park, Jun-Hwan, et al.
Publicado: (2017)

Determination of Thymol in Commercial Formulation, Essential Oils, Traditional, and Ultrasound-Based Extracts of Thymus vulgaris and Origanum vulgare Using a Greener HPTLC Approach
por: Foudah, Ahmed I., et al.
Publicado: (2022)

Novel role of STRAP in progression and metastasis of colorectal cancer through Wnt/β-catenin signaling
por: Yuan, Guandou, et al.
Publicado: (2016)

Targeting ADAR1 suppresses progression and peritoneal metastasis of gastric cancer through Wnt / β-catenin pathway
por: Li, Zhiyong, et al.
Publicado: (2021)

The Chalcone Lonchocarpin Inhibits Wnt/β-Catenin Signaling and Suppresses Colorectal Cancer Proliferation
por: Predes, Danilo, et al.
Publicado: (2019)

FUT2 promotes the tumorigenicity and metastasis of colorectal cancer cells via the Wnt/β-catenin pathway
por: Liu, Peng, et al.
Publicado: (2023)

Running Against the Wnt: How Wnt/β-Catenin Suppresses Adipogenesis
por: de Winter, Twan J. J., et al.
Publicado: (2021)

Wnt2 complements Wnt/β-catenin signaling in colorectal cancer
por: Jung, Youn-Sang, et al.
Publicado: (2015)

Symes on Thymol and Thymol Camphor
Publicado: (1879)

SPARCL1 suppresses osteosarcoma metastasis and recruits macrophages by activation of canonical WNT/β-catenin signaling through stabilization of the WNT–receptor complex
por: Zhao, S-J, et al.
Publicado: (2018)

WDR74 promotes proliferation and metastasis in colorectal cancer cells through regulating the Wnt/β-catenin signaling pathway
por: Cai, Zhou, et al.
Publicado: (2021)

MicroRNA-200a suppresses the Wnt/β-catenin signaling pathway by interacting with β-catenin
por: SU, JUAN, et al.
Publicado: (2011)

(−)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway
por: Chen, Yue, et al.
Publicado: (2017)

YPEL3 suppresses epithelial–mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway
por: Zhang, Jian, et al.
Publicado: (2016)

Role of Wnt/β-Catenin Signaling in the Chemoresistance Modulation of Colorectal Cancer
por: Yuan, Shengli, et al.
Publicado: (2020)

RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer
por: Li, Qingyuan, et al.
Publicado: (2019)

Benzyl isothiocyanate suppresses development and metastasis of murine mammary carcinoma by regulating the Wnt/β-catenin pathway
por: Xie, Bei, et al.
Publicado: (2019)

Blockade of Wnt/β-catenin signaling suppresses breast cancer metastasis by inhibiting CSC-like phenotype
por: Jang, Gyu-Beom, et al.
Publicado: (2015)

Benzyl isothiocyanate suppresses development and metastasis of murine mammary carcinoma by regulating the Wnt/β-catenin pathway
por: Xie, Bei, et al.
Publicado: (2022)

DDAH1 mediates gastric cancer cell invasion and metastasis via Wnt/β‐catenin signaling pathway
por: Ye, Jianxin, et al.
Publicado: (2017)

HMGB1 Promotes the Proliferation and Metastasis of Lung Cancer by Activating the Wnt/β-Catenin Pathway
por: Wang, Xiao-hui, et al.
Publicado: (2020)

miR-885-5p suppresses hepatocellular carcinoma metastasis and inhibits Wnt/β-catenin signaling pathway
por: Zhang, Zhuhong, et al.
Publicado: (2016)

Oncolytic Adenovirus CD55-Smad4 Suppresses Cell Proliferation, Metastasis, and Tumor Stemness in Colorectal Cancer by Regulating Wnt/β-Catenin Signaling Pathway
por: Xiao, Boduan, et al.
Publicado: (2020)

C644‐0303, a small‐molecule inhibitor of the Wnt/β‐catenin pathway, suppresses colorectal cancer growth
por: Yan, Yu, et al.
Publicado: (2021)

Wnt and β-Catenin Signaling in the Bone Metastasis of Prostate Cancer
por: Kaplan, Zachary, et al.
Publicado: (2021)

Wnt signaling modulator DKK4 inhibits colorectal cancer metastasis through an AKT/Wnt/β-catenin negative feedback pathway
por: Liang, Junrong, et al.
Publicado: (2022)

Thymol
Publicado: (1878)

MicroRNA-384 inhibits nasopharyngeal carcinoma growth and metastasis via binding to Smad5 and suppressing the Wnt/β-catenin axis
por: Zeng, Xinyu, et al.
Publicado: (2021)

Piperine suppresses the Wnt/β-catenin pathway and has anti-cancer effects on colorectal cancer cells
por: de Almeida, Gracielle C., et al.
Publicado: (2020)

Curcumin suppresses colorectal tumorigenesis via the Wnt/β-catenin signaling pathway by downregulating Axin2
por: Hao, Jiaxue, et al.
Publicado: (2021)

FXR suppresses colorectal cancer by inhibiting the Wnt/β-catenin pathway via activation of TLE3
por: Dong, Xingchen, et al.
Publicado: (2022)

Correction to: YPEL3 suppresses epithelial–mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway
por: Zhang, Jian, et al.
Publicado: (2020)

Correction to: YPEL3 suppresses epithelial–mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway
por: Zhang, Jian, et al.
Publicado: (2021)

Alantolactone inhibits proliferation, metastasis and promotes apoptosis of human osteosarcoma cells by suppressing Wnt/β-catenin and MAPKs signaling pathways
por: Yang, Chunmei, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ka17vic3vtsuua5stqhquab6a6