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Measurements of the Timescale and Conformational Space of AMPA Receptor Desensitization

Ionotropic glutamate receptors are ligand-gated ion channels that mediate excitatory synaptic transmission in the central nervous system. Desensitization of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid subtype after glutamate binding appears critical for brain function and involves rearr...

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Detalles Bibliográficos
Autores principales: Salazar, Hector, Mischke, Sabrina, Plested, Andrew J.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335938/
https://www.ncbi.nlm.nih.gov/pubmed/32559412
http://dx.doi.org/10.1016/j.bpj.2020.05.029