Cargando…
Pulsed Electric Fields Can Create Pores in the Voltage Sensors of Voltage-Gated Ion Channels
Pulsed electric fields are increasingly used in medicine to transiently increase the cell membrane permeability via electroporation to deliver therapeutic molecules into the cell. One type of event that contributes to this increase in membrane permeability is the formation of pores in the membrane l...
Autores principales: | Rems, Lea, Kasimova, Marina A., Testa, Ilaria, Delemotte, Lucie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335976/ https://www.ncbi.nlm.nih.gov/pubmed/32559411 http://dx.doi.org/10.1016/j.bpj.2020.05.030 |
Ejemplares similares
-
An open state of a voltage-gated sodium channel involving a π-helix and conserved pore-facing asparagine
por: Choudhury, Koushik, et al.
Publicado: (2022) -
Molecular Dynamics Simulations of Voltage-Gated Cation Channels: Insights on Voltage-Sensor Domain Function and Modulation
por: Delemotte, Lucie, et al.
Publicado: (2012) -
Voltage-Dependent Gating in a “Voltage Sensor-Less” Ion Channel
por: Kurata, Harley T., et al.
Publicado: (2010) -
Determining the molecular basis of voltage sensitivity in membrane proteins
por: Kasimova, Marina A., et al.
Publicado: (2018) -
The pore of voltage-gated potassium ion channels is strained when closed
por: Fowler, Philip W., et al.
Publicado: (2013)