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Notified dengue deaths in Myanmar (2017-18): profile and diagnosis delays

Background: Complications in dengue usually occur between day four and day six after fever onset. Hence, early diagnosis and haematological monitoring are vital. Among all hospital reported dengue deaths in Myanmar in 2017-18, we assessed the i) patient profile, ii) proportion of patients who arrive...

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Autores principales: Linn, Nwe Ni, Kyaw, Khine Wut Yee, Shewade, Hemant Deepak, Kyaw, Aye Mon Mon, Tun, Myat Min, Khine, San Kyawt, Linn, Nay Yi Yi, Thi, Aung, Lin, Zaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336047/
https://www.ncbi.nlm.nih.gov/pubmed/32724563
http://dx.doi.org/10.12688/f1000research.23699.1
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author Linn, Nwe Ni
Kyaw, Khine Wut Yee
Shewade, Hemant Deepak
Kyaw, Aye Mon Mon
Tun, Myat Min
Khine, San Kyawt
Linn, Nay Yi Yi
Thi, Aung
Lin, Zaw
author_facet Linn, Nwe Ni
Kyaw, Khine Wut Yee
Shewade, Hemant Deepak
Kyaw, Aye Mon Mon
Tun, Myat Min
Khine, San Kyawt
Linn, Nay Yi Yi
Thi, Aung
Lin, Zaw
author_sort Linn, Nwe Ni
collection PubMed
description Background: Complications in dengue usually occur between day four and day six after fever onset. Hence, early diagnosis and haematological monitoring are vital. Among all hospital reported dengue deaths in Myanmar in 2017-18, we assessed the i) patient profile, ii) proportion of patients who arrived with a dengue diagnosis at admission and iii) delays in diagnosis after fever onset. Methods: This was a descriptive study involving secondary data. For all the notified deaths, death investigation forms were not available in prescribed format and therefore, data were extracted from hospital case records.  Results: Of 304 deaths, 184 (60.5%) were female and 233 (76.6%) were less than 10 years old. Township level hospitals or below reported 36 deaths (11.8%) and the remaining deaths were from higher level facilities. Dengue was diagnosed before admission in 26 (8.5%) people and 169 (55.6%) were in shock at admission. Of 208 with date of fever onset recorded, the median diagnosis delay was four (interquartile range-IQR: 3, 5) days. Patient level delay (median three days) was a major contributor to the diagnosis delay. Conclusions: Most of the patients who died did not have a diagnosis of dengue before admission. This calls for an urgent review of health system preparedness in peripheral health facilities to suspect, diagnose, monitor, refer and treat dengue in children and patient level factors for better understanding of the reasons of delay. Timely filling of death investigation forms in a prescribed format and quarterly death reviews based on these is recommended.
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spelling pubmed-73360472020-07-27 Notified dengue deaths in Myanmar (2017-18): profile and diagnosis delays Linn, Nwe Ni Kyaw, Khine Wut Yee Shewade, Hemant Deepak Kyaw, Aye Mon Mon Tun, Myat Min Khine, San Kyawt Linn, Nay Yi Yi Thi, Aung Lin, Zaw F1000Res Research Article Background: Complications in dengue usually occur between day four and day six after fever onset. Hence, early diagnosis and haematological monitoring are vital. Among all hospital reported dengue deaths in Myanmar in 2017-18, we assessed the i) patient profile, ii) proportion of patients who arrived with a dengue diagnosis at admission and iii) delays in diagnosis after fever onset. Methods: This was a descriptive study involving secondary data. For all the notified deaths, death investigation forms were not available in prescribed format and therefore, data were extracted from hospital case records.  Results: Of 304 deaths, 184 (60.5%) were female and 233 (76.6%) were less than 10 years old. Township level hospitals or below reported 36 deaths (11.8%) and the remaining deaths were from higher level facilities. Dengue was diagnosed before admission in 26 (8.5%) people and 169 (55.6%) were in shock at admission. Of 208 with date of fever onset recorded, the median diagnosis delay was four (interquartile range-IQR: 3, 5) days. Patient level delay (median three days) was a major contributor to the diagnosis delay. Conclusions: Most of the patients who died did not have a diagnosis of dengue before admission. This calls for an urgent review of health system preparedness in peripheral health facilities to suspect, diagnose, monitor, refer and treat dengue in children and patient level factors for better understanding of the reasons of delay. Timely filling of death investigation forms in a prescribed format and quarterly death reviews based on these is recommended. F1000 Research Limited 2020-06-09 /pmc/articles/PMC7336047/ /pubmed/32724563 http://dx.doi.org/10.12688/f1000research.23699.1 Text en Copyright: © 2020 Linn NN et al. https://creativecommons.org/licenses/by/3.0/igo/ This is an open access article distributed under the terms of the Creative Commons Attribution IGO Licence.
spellingShingle Research Article
Linn, Nwe Ni
Kyaw, Khine Wut Yee
Shewade, Hemant Deepak
Kyaw, Aye Mon Mon
Tun, Myat Min
Khine, San Kyawt
Linn, Nay Yi Yi
Thi, Aung
Lin, Zaw
Notified dengue deaths in Myanmar (2017-18): profile and diagnosis delays
title Notified dengue deaths in Myanmar (2017-18): profile and diagnosis delays
title_full Notified dengue deaths in Myanmar (2017-18): profile and diagnosis delays
title_fullStr Notified dengue deaths in Myanmar (2017-18): profile and diagnosis delays
title_full_unstemmed Notified dengue deaths in Myanmar (2017-18): profile and diagnosis delays
title_short Notified dengue deaths in Myanmar (2017-18): profile and diagnosis delays
title_sort notified dengue deaths in myanmar (2017-18): profile and diagnosis delays
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336047/
https://www.ncbi.nlm.nih.gov/pubmed/32724563
http://dx.doi.org/10.12688/f1000research.23699.1
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