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Continuous capture of recombinant antibodies by ZnCl(2) precipitation without polyethylene glycol
The capture of recombinant antibodies from cell culture broth is the first critical step of downstream processing. We were able to develop a precipitation‐based method for the capture and purification of monoclonal antibodies based on divalent cations, namely ZnCl(2). Traditional precipitation proce...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336134/ https://www.ncbi.nlm.nih.gov/pubmed/32647505 http://dx.doi.org/10.1002/elsc.201900160 |