SIRT1–NOX4 signaling axis regulates cancer cachexia

Approximately one third of cancer patients die due to complexities related to cachexia. However, the mechanisms of cachexia and the potential therapeutic interventions remain poorly studied. We observed a significant positive correlation between SIRT1 expression and muscle fiber cross-sectional area...

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Detalles Bibliográficos
Autores principales: Dasgupta, Aneesha, Shukla, Surendra K., Vernucci, Enza, King, Ryan J., Abrego, Jaime, Mulder, Scott E., Mullen, Nicholas J., Graves, Gavin, Buettner, Kyla, Thakur, Ravi, Murthy, Divya, Attri, Kuldeep S., Wang, Dezhen, Chaika, Nina V., Pacheco, Camila G., Rai, Ibha, Engle, Dannielle D., Grandgenett, Paul M., Punsoni, Michael, Reames, Bradley N., Teoh-Fitzgerald, Melissa, Oberley-Deegan, Rebecca, Yu, Fang, Klute, Kelsey A., Hollingsworth, Michael A., Zimmerman, Matthew C., Mehla, Kamiya, Sadoshima, Junichi, Tuveson, David A., Singh, Pankaj K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336299/
https://www.ncbi.nlm.nih.gov/pubmed/32441762
http://dx.doi.org/10.1084/jem.20190745

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