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Efficient gene knockout in primary human and murine myeloid cells by non-viral delivery of CRISPR-Cas9
Myeloid cells play critical and diverse roles in mammalian physiology, including tissue development and repair, innate defense against pathogens, and generation of adaptive immunity. As cells that show prolonged recruitment to sites of injury or pathology, myeloid cells represent therapeutic targets...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336301/ https://www.ncbi.nlm.nih.gov/pubmed/32357367 http://dx.doi.org/10.1084/jem.20191692 |