Cargando…

TRIM24 facilitates antiviral immunity through mediating K63-linked TRAF3 ubiquitination

Ubiquitination is an essential mechanism in the control of antiviral immunity upon virus infection. Here, we identify a series of ubiquitination-modulating enzymes that are modulated by vesicular stomatitis virus (VSV). Notably, TRIM24 is down-regulated through direct transcriptional suppression ind...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Qingchen, Yu, Tao, Gan, Shucheng, Wang, Yan, Pei, Yifei, Zhao, Qifan, Pei, Siyu, Hao, Shumeng, Yuan, Jia, Xu, Jing, Hou, Fajian, Wu, Xuefeng, Peng, Chao, Wu, Ping, Qin, Jun, Xiao, Yichuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336305/ https://www.ncbi.nlm.nih.gov/pubmed/32324863 http://dx.doi.org/10.1084/jem.20192083

Ejemplares similares

Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24
por: Yu, Tao, et al.
Publicado: (2019)

TRIM47 is a novel endothelial activation factor that aggravates lipopolysaccharide-induced acute lung injury in mice via K63-linked ubiquitination of TRAF2
por: Qian, Yisong, et al.
Publicado: (2022)

TRAF6 directs FOXP3 localization and facilitates regulatory T‐cell function through K63‐linked ubiquitination
por: Ni, Xuhao, et al.
Publicado: (2019)

K63-linked ubiquitination of DYRK1A by TRAF2 alleviates Sprouty 2-mediated degradation of EGFR
por: Zhang, Pengshan, et al.
Publicado: (2021)

Transcriptional activator TAp63 is upregulated in muscular atrophy during ALS and induces the pro-atrophic ubiquitin ligase Trim63
por: von Grabowiecki, Yannick, et al.
Publicado: (2016)

TRIM21 suppresses CHK1 activation by preferentially targeting CLASPIN for K63-linked ubiquitination
por: Zhu, Xuefei, et al.
Publicado: (2022)

Elucidation of TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes
por: Yang, Emily, et al.
Publicado: (2022)

The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity
por: Huang, Xinfang, et al.
Publicado: (2021)

TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity
por: Lang, Xueting, et al.
Publicado: (2017)

LncNSPL facilitates influenza A viral immune escape by restricting TRIM25-mediated K63-linked RIG-I ubiquitination
por: Jiang, Jingjing, et al.
Publicado: (2022)

SARS-CoV-2 Nsp8 suppresses MDA5 antiviral immune responses by impairing TRIM4-mediated K63-linked polyubiquitination
por: Zhang, Xiaolin, et al.
Publicado: (2023)

Regulation of MDA5-MAVS Antiviral Signaling Axis by TRIM25 through TRAF6-Mediated NF-κB Activation
por: Lee, Na-Rae, et al.
Publicado: (2015)

TRAF6 Promotes PRMT5 Activity in a Ubiquitination-Dependent Manner
por: Liu, Liu, et al.
Publicado: (2023)

To Ubiquitinate or Not to Ubiquitinate: TRIM17 in Cell Life and Death
por: Basu-Shrivastava, Meenakshi, et al.
Publicado: (2021)

TRIM5α requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription
por: Fletcher, Adam J, et al.
Publicado: (2015)

The E3 ligase TRIM26 suppresses ferroptosis through catalyzing K63-linked ubiquitination of GPX4 in glioma
por: Wang, Zhangjie, et al.
Publicado: (2023)

Origin and Diversification of TRIM Ubiquitin Ligases
por: Marín, Ignacio
Publicado: (2012)

Nucleocapsid protein of porcine reproductive and respiratory syndrome virus antagonizes the antiviral activity of TRIM25 by interfering with TRIM25-mediated RIG-I ubiquitination
por: Zhao, Kuan, et al.
Publicado: (2019)

RTN3 inhibits RIG-I-mediated antiviral responses by impairing TRIM25-mediated K63-linked polyubiquitination
por: Yang, Ziwei, et al.
Publicado: (2021)

A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases
por: Kiss, Leo, et al.
Publicado: (2019)

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53
por: Guo, Yafei, et al.
Publicado: (2021)

TRAF6 regulates melanoma invasion and metastasis through ubiquitination of Basigin
por: Luo, Zhongling, et al.
Publicado: (2016)

Structural insights into the TRIM family of ubiquitin E3 ligases
por: Li, Yang, et al.
Publicado: (2014)

K63 ubiquitination in immune signaling
por: Madiraju, Charitha, et al.
Publicado: (2022)

Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1
por: Zang, Lichao, et al.
Publicado: (2022)

Correction: RTN3 inhibits RIG-I-mediated antiviral responses by impairing TRIM25-mediated K63-linked polyubiquitination
por: Yang, Ziwei, et al.
Publicado: (2021)

TRIM58 functions as a tumor suppressor in colorectal cancer by promoting RECQL4 ubiquitination to inhibit the AKT signaling pathway
por: Sun, Naizhi, et al.
Publicado: (2023)

Ubiquitination, Biotech Startups, and the Future of TRIM Family Proteins: A TRIM-Endous Opportunity
por: Bhaduri, Utsa, et al.
Publicado: (2021)

TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away
por: Mevissen, Tycho E.T., et al.
Publicado: (2023)

MuRF1/TRIM63, Master Regulator of Muscle Mass
por: Peris-Moreno, Dulce, et al.
Publicado: (2020)

Mutations in TRIM63 cause an autosomal-recessive form of hypertrophic cardiomyopathy
por: Salazar-Mendiguchía, Joel, et al.
Publicado: (2020)

USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA
por: Ye, Liya, et al.
Publicado: (2019)

TRAF4-mediated ubiquitination-dependent activation of JNK/Bcl-xL drives radioresistance
por: Dong, Xin, et al.
Publicado: (2023)

TRIM37 Augments AP-2γ Transcriptional Activity and Cellular Localization via K63-linked Ubiquitination to Drive Breast Cancer Progression
por: Cui, Guimei, et al.
Publicado: (2022)

The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome System
por: Armstrong, Stephen R., et al.
Publicado: (2016)

Tissue-specific metabolism and TRIM24
por: Thakkar, Kaushik N., et al.
Publicado: (2015)

The Role of TRIM24 in Allergic Rhinitis
por: Yang, Seung Koo, et al.
Publicado: (2023)

TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitination
por: Ma, Qinmei, et al.
Publicado: (2023)

Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response
por: Zhao, Kai, et al.
Publicado: (2016)

Energy Loss and Radial Force Variation Caused by Impeller Trimming in a Double-Suction Centrifugal Pump
por: Deng, Qifan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_858219pgq1ec3nljnadgn2c30n