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Proline/alanine-rich sequence (PAS) polypeptides as an alternative to PEG precipitants for protein crystallization
Proline/alanine-rich sequence (PAS) polypeptides represent a novel class of biosynthetic polymers comprising repetitive sequences of the small proteinogenic amino acids l-proline, l-alanine and/or l-serine. PAS polymers are strongly hydrophilic and highly soluble in water, where they exhibit a nativ...
Autores principales: | Schiefner, André, Walser, Rebecca, Gebauer, Michaela, Skerra, Arne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336357/ https://www.ncbi.nlm.nih.gov/pubmed/32627748 http://dx.doi.org/10.1107/S2053230X20008328 |
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