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Structure of apo flavin-dependent halogenase Xcc4156 hints at a reason for cofactor-soaking difficulties

Flavin-dependent halogenases regioselectively introduce halide substituents into electron-rich substrates under mild reaction conditions. For the enzyme Xcc4156 from Xanthomonas campestris, the structure of a complex with the cofactor flavin adenine dinucleotide (FAD) and a bromide ion would be of p...

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Detalles Bibliográficos
Autores principales: Widmann, Christiane, Ismail, Mohamed, Sewald, Norbert, Niemann, Hartmut H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336383/
https://www.ncbi.nlm.nih.gov/pubmed/32627741
http://dx.doi.org/10.1107/S2059798320007731