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Structure of apo flavin-dependent halogenase Xcc4156 hints at a reason for cofactor-soaking difficulties
Flavin-dependent halogenases regioselectively introduce halide substituents into electron-rich substrates under mild reaction conditions. For the enzyme Xcc4156 from Xanthomonas campestris, the structure of a complex with the cofactor flavin adenine dinucleotide (FAD) and a bromide ion would be of p...
Autores principales: | Widmann, Christiane, Ismail, Mohamed, Sewald, Norbert, Niemann, Hartmut H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336383/ https://www.ncbi.nlm.nih.gov/pubmed/32627741 http://dx.doi.org/10.1107/S2059798320007731 |
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