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Statistical driver genes as a means to uncover missing heritability for age-related macular degeneration

BACKGROUND: Age-related macular degeneration (AMD) is a progressive retinal disease contributing to blindness worldwide. Multiple estimates for AMD heritability (h(2)) exist; however, a substantial proportion of h(2) is not attributable to known genomic loci. The International AMD Genomics Consortiu...

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Detalles Bibliográficos
Autores principales:	Waksmunski, Andrea R., Grunin, Michelle, Kinzy, Tyler G., Igo, Robert P., Haines, Jonathan L., Cooke Bailey, Jessica N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336430/ https://www.ncbi.nlm.nih.gov/pubmed/32631374 http://dx.doi.org/10.1186/s12920-020-00747-4

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