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Decoding the evolutionary response to prostate cancer therapy by plasma genome sequencing

BACKGROUND: Investigating genome evolution in response to therapy is difficult in human tissue samples. To address this challenge, we develop an unbiased whole-genome plasma DNA sequencing approach that concurrently measures genomic copy number and exome mutations from archival cryostored plasma sam...

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Detalles Bibliográficos
Autores principales:	Ramesh, Naveen, Sei, Emi, Tsai, Pei Ching, Bai, Shanshan, Zhao, Yuehui, Troncoso, Patricia, Corn, Paul G., Logothetis, Christopher, Zurita, Amado J., Navin, Nicholas E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336456/ https://www.ncbi.nlm.nih.gov/pubmed/32631448 http://dx.doi.org/10.1186/s13059-020-02045-9

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