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Metformin inhibits cervical cancer cell proliferation by modulating PI3K/Akt-induced major histocompatibility complex class I-related chain A gene expression

BACKGROUND: Recent studies have shown that the classic hypoglycemic drug metformin inhibits tumor growth; however, the underlying mechanism remains unclear. We previously showed that metformin disrupts the sponge effect of long non-coding RNA MALAT1/miR-142-3p to inhibit cervical cancer cell prolife...

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Detalles Bibliográficos
Autores principales: Xia, Chenglai, Liu, Chang, He, Zhihong, Cai, Yantao, Chen, Jinman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336474/
https://www.ncbi.nlm.nih.gov/pubmed/32631421
http://dx.doi.org/10.1186/s13046-020-01627-6