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Mediastinal Actinomycosis After Esophagogastroduodenoscopy

Actinomycosis is an uncommon bacterial infection that presents as an indolent, progressive disease that can affect multiple organ systems. We describe the case of a 66-year-old female with end-stage renal disease who presented to the emergency department after developing acute dyspnea and chest pain...

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Autores principales: Thrun, Connor S, Boster, Joshua, Jansen, Nathan, Dado, David, Okulicz, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336692/
https://www.ncbi.nlm.nih.gov/pubmed/32642339
http://dx.doi.org/10.7759/cureus.8423
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author Thrun, Connor S
Boster, Joshua
Jansen, Nathan
Dado, David
Okulicz, Jason
author_facet Thrun, Connor S
Boster, Joshua
Jansen, Nathan
Dado, David
Okulicz, Jason
author_sort Thrun, Connor S
collection PubMed
description Actinomycosis is an uncommon bacterial infection that presents as an indolent, progressive disease that can affect multiple organ systems. We describe the case of a 66-year-old female with end-stage renal disease who presented to the emergency department after developing acute dyspnea and chest pain two weeks after undergoing a diagnostic esophagogastroduodenoscopy (EGD). A CT scan was obtained that revealed a large mediastinal mass, which was initially concerning for a potential malignancy. Biopsy of the mass and Gram stain was consistent with mediastinal actinomycosis. The patient was subsequently treated with an extended course of antibiotics that resulted in significant clinical improvement. Previously reported cases describing a correlation between EGD and mediastinal actinomycosis have been associated with invasive procedures such as esophageal stent placement and transesophageal biopsy. We describe a case of an uncommon infectious complication of a diagnostic EGD that was not associated with intentional mucosal disruption.
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spelling pubmed-73366922020-07-07 Mediastinal Actinomycosis After Esophagogastroduodenoscopy Thrun, Connor S Boster, Joshua Jansen, Nathan Dado, David Okulicz, Jason Cureus Internal Medicine Actinomycosis is an uncommon bacterial infection that presents as an indolent, progressive disease that can affect multiple organ systems. We describe the case of a 66-year-old female with end-stage renal disease who presented to the emergency department after developing acute dyspnea and chest pain two weeks after undergoing a diagnostic esophagogastroduodenoscopy (EGD). A CT scan was obtained that revealed a large mediastinal mass, which was initially concerning for a potential malignancy. Biopsy of the mass and Gram stain was consistent with mediastinal actinomycosis. The patient was subsequently treated with an extended course of antibiotics that resulted in significant clinical improvement. Previously reported cases describing a correlation between EGD and mediastinal actinomycosis have been associated with invasive procedures such as esophageal stent placement and transesophageal biopsy. We describe a case of an uncommon infectious complication of a diagnostic EGD that was not associated with intentional mucosal disruption. Cureus 2020-06-03 /pmc/articles/PMC7336692/ /pubmed/32642339 http://dx.doi.org/10.7759/cureus.8423 Text en Copyright © 2020, Thrun et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Thrun, Connor S
Boster, Joshua
Jansen, Nathan
Dado, David
Okulicz, Jason
Mediastinal Actinomycosis After Esophagogastroduodenoscopy
title Mediastinal Actinomycosis After Esophagogastroduodenoscopy
title_full Mediastinal Actinomycosis After Esophagogastroduodenoscopy
title_fullStr Mediastinal Actinomycosis After Esophagogastroduodenoscopy
title_full_unstemmed Mediastinal Actinomycosis After Esophagogastroduodenoscopy
title_short Mediastinal Actinomycosis After Esophagogastroduodenoscopy
title_sort mediastinal actinomycosis after esophagogastroduodenoscopy
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336692/
https://www.ncbi.nlm.nih.gov/pubmed/32642339
http://dx.doi.org/10.7759/cureus.8423
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