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SARS-CoV2 drives JAK1/2-dependent local and systemic complement hyperactivation
Patients with coronavirus disease 2019 (COVID-19) present with a range of devastating acute clinical manifestations affecting the lungs, liver, kidneys and gut. The best-characterized entry receptor for the disease-causing virus SARS-CoV2, angiotensin converting enzyme (ACE) 2, is highly expressed i...
Autores principales: | Yan, Bingyu, Freiwald, Tilo, Chauss, Daniel, Wang, Luopin, West, Erin, Bibby, Jack, Olson, Matthew, Kordasti, Shahram, Portilla, Didier, Laurence, Arian, Lionakis, Michail S, Kemper, Claudia, Afzali, Behdad, Kazemian, Majid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336704/ https://www.ncbi.nlm.nih.gov/pubmed/32702726 http://dx.doi.org/10.21203/rs.3.rs-33390/v1 |
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