Structural analysis of missense mutations occurring in the DNA-binding domain of HSF4 associated with congenital cataracts

Congenital cataract (CC) is the major cause of childish blindness, and nearly 50% of CCs are hereditary disorders. HSF4, a member of the heat shock transcription factor family, acts as a key regulator of cell growth and differentiation during the development of sensory organs. Missense mutations in...

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Detalles Bibliográficos
Autores principales: Xiao, Zaiyu, Guo, Ling, Zhang, Yang, Cui, Liwei, Dai, Yujie, Lan, Zhu, Zhang, Qinghua, Wang, Sheng, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337047/
https://www.ncbi.nlm.nih.gov/pubmed/32647819
http://dx.doi.org/10.1016/j.yjsbx.2019.100015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337047/
https://www.ncbi.nlm.nih.gov/pubmed/32647819
http://dx.doi.org/10.1016/j.yjsbx.2019.100015

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