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Structural basis for differentiation between two classes of thiolase: Degradative vs biosynthetic thiolase
Thiolases are a well characterized family of enzymes with two distinct categories: degradative, β-ketoadipyl-CoA thiolases and biosynthetic, acetoacetyl-CoA thiolases. Both classes share an identical catalytic triad but catalyze reactions in opposite directions. Moreover, it is established that in c...
Autores principales: | Bhaskar, Sukritee, Steer, David L., Anand, Ruchi, Panjikar, Santosh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337054/ https://www.ncbi.nlm.nih.gov/pubmed/32647822 http://dx.doi.org/10.1016/j.yjsbx.2019.100018 |
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