Small angle X-ray scattering and molecular dynamic simulations provide molecular insight for stability of recombinant human transferrin

Transferrin is an attractive candidate for drug delivery due to its ability to cross the blood brain barrier. However, in order to be able to use it for therapeutic purposes, it is important to investigate how its stability depends on different formulation conditions. Combining high-throughput therm...

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Detalles Bibliográficos
Autores principales: Kulakova, Alina, Indrakumar, Sowmya, Sønderby, Pernille, Gentiluomo, Lorenzo, Streicher, Werner, Roessner, Dierk, Frieß, Wolfgang, Peters, Günther H.J., Harris, Pernille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337065/
https://www.ncbi.nlm.nih.gov/pubmed/32647821
http://dx.doi.org/10.1016/j.yjsbx.2019.100017

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