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Genetically encoded betaxanthin-based small-molecular fluorescent reporter for mammalian cells
We designed and engineered a dye production cassette encoding a heterologous pathway, including human tyrosine hydroxylase and Amanita muscaria 4,5-DOPA dioxygenase, for the biosynthesis of the betaxanthin family of plant and fungal pigments in mammalian cells. The system does not impair cell viabil...
Autores principales: | Stücheli, Pascal, Sieber, Simon, Fuchs, David W, Scheller, Leo, Strittmatter, Tobias, Saxena, Pratik, Gademann, Karl, Fussenegger, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337513/ https://www.ncbi.nlm.nih.gov/pubmed/32421771 http://dx.doi.org/10.1093/nar/gkaa342 |
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