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Translation at first sight: the influence of leading codons

First triplets of mRNA coding region affect the yield of translation. We have applied the flowseq method to analyze >30 000 variants of the codons 2–11 of the fluorescent protein reporter to identify factors affecting the protein synthesis. While the negative influence of mRNA secondary structure...

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Detalles Bibliográficos
Autores principales:	Osterman, Ilya A, Chervontseva, Zoe S, Evfratov, Sergey A, Sorokina, Alena V, Rodin, Vladimir A, Rubtsova, Maria P, Komarova, Ekaterina S, Zatsepin, Timofei S, Kabilov, Marsel R, Bogdanov, Alexey A, Gelfand, Mikhail S, Dontsova, Olga A, Sergiev, Petr V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337518/ https://www.ncbi.nlm.nih.gov/pubmed/32427319 http://dx.doi.org/10.1093/nar/gkaa430

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