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Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2

We enrolled 91 consecutive inpatients with COVID-19 at 6 hospitals in Toronto, Canada, and tested 1 nasopharyngeal swab/saliva sample pair from each patient using real-time RT-PCR for severe acute respiratory syndrome coronavirus 2. Sensitivity was 89% for nasopharyngeal swabs and 72% for saliva (P ...

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Autores principales: Jamal, Alainna J, Mozafarihashjin, Mohammad, Coomes, Eric, Powis, Jeff, Li, Angel X, Paterson, Aimee, Anceva-Sami, Sofia, Barati, Shiva, Crowl, Gloria, Faheem, Amna, Farooqi, Lubna, Khan, Saman, Prost, Karren, Poutanen, Susan, Taylor, Maureen, Yip, Lily, Zhong, Xi Zoe, McGeer, Allison J, Mubareka, Samira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337630/
https://www.ncbi.nlm.nih.gov/pubmed/32584972
http://dx.doi.org/10.1093/cid/ciaa848
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author Jamal, Alainna J
Mozafarihashjin, Mohammad
Coomes, Eric
Powis, Jeff
Li, Angel X
Paterson, Aimee
Anceva-Sami, Sofia
Barati, Shiva
Crowl, Gloria
Faheem, Amna
Farooqi, Lubna
Khan, Saman
Prost, Karren
Poutanen, Susan
Taylor, Maureen
Yip, Lily
Zhong, Xi Zoe
McGeer, Allison J
Mubareka, Samira
author_facet Jamal, Alainna J
Mozafarihashjin, Mohammad
Coomes, Eric
Powis, Jeff
Li, Angel X
Paterson, Aimee
Anceva-Sami, Sofia
Barati, Shiva
Crowl, Gloria
Faheem, Amna
Farooqi, Lubna
Khan, Saman
Prost, Karren
Poutanen, Susan
Taylor, Maureen
Yip, Lily
Zhong, Xi Zoe
McGeer, Allison J
Mubareka, Samira
author_sort Jamal, Alainna J
collection PubMed
description We enrolled 91 consecutive inpatients with COVID-19 at 6 hospitals in Toronto, Canada, and tested 1 nasopharyngeal swab/saliva sample pair from each patient using real-time RT-PCR for severe acute respiratory syndrome coronavirus 2. Sensitivity was 89% for nasopharyngeal swabs and 72% for saliva (P = .02). Difference in sensitivity was greatest for sample pairs collected later in illness.
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spelling pubmed-73376302020-07-08 Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2 Jamal, Alainna J Mozafarihashjin, Mohammad Coomes, Eric Powis, Jeff Li, Angel X Paterson, Aimee Anceva-Sami, Sofia Barati, Shiva Crowl, Gloria Faheem, Amna Farooqi, Lubna Khan, Saman Prost, Karren Poutanen, Susan Taylor, Maureen Yip, Lily Zhong, Xi Zoe McGeer, Allison J Mubareka, Samira Clin Infect Dis Brief Reports We enrolled 91 consecutive inpatients with COVID-19 at 6 hospitals in Toronto, Canada, and tested 1 nasopharyngeal swab/saliva sample pair from each patient using real-time RT-PCR for severe acute respiratory syndrome coronavirus 2. Sensitivity was 89% for nasopharyngeal swabs and 72% for saliva (P = .02). Difference in sensitivity was greatest for sample pairs collected later in illness. Oxford University Press 2020-06-25 /pmc/articles/PMC7337630/ /pubmed/32584972 http://dx.doi.org/10.1093/cid/ciaa848 Text en © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com. https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)
spellingShingle Brief Reports
Jamal, Alainna J
Mozafarihashjin, Mohammad
Coomes, Eric
Powis, Jeff
Li, Angel X
Paterson, Aimee
Anceva-Sami, Sofia
Barati, Shiva
Crowl, Gloria
Faheem, Amna
Farooqi, Lubna
Khan, Saman
Prost, Karren
Poutanen, Susan
Taylor, Maureen
Yip, Lily
Zhong, Xi Zoe
McGeer, Allison J
Mubareka, Samira
Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2
title Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2
title_full Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2
title_fullStr Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2
title_full_unstemmed Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2
title_short Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2
title_sort sensitivity of nasopharyngeal swabs and saliva for the detection of severe acute respiratory syndrome coronavirus 2
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337630/
https://www.ncbi.nlm.nih.gov/pubmed/32584972
http://dx.doi.org/10.1093/cid/ciaa848
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