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Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2
We enrolled 91 consecutive inpatients with COVID-19 at 6 hospitals in Toronto, Canada, and tested 1 nasopharyngeal swab/saliva sample pair from each patient using real-time RT-PCR for severe acute respiratory syndrome coronavirus 2. Sensitivity was 89% for nasopharyngeal swabs and 72% for saliva (P ...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337630/ https://www.ncbi.nlm.nih.gov/pubmed/32584972 http://dx.doi.org/10.1093/cid/ciaa848 |
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author | Jamal, Alainna J Mozafarihashjin, Mohammad Coomes, Eric Powis, Jeff Li, Angel X Paterson, Aimee Anceva-Sami, Sofia Barati, Shiva Crowl, Gloria Faheem, Amna Farooqi, Lubna Khan, Saman Prost, Karren Poutanen, Susan Taylor, Maureen Yip, Lily Zhong, Xi Zoe McGeer, Allison J Mubareka, Samira |
author_facet | Jamal, Alainna J Mozafarihashjin, Mohammad Coomes, Eric Powis, Jeff Li, Angel X Paterson, Aimee Anceva-Sami, Sofia Barati, Shiva Crowl, Gloria Faheem, Amna Farooqi, Lubna Khan, Saman Prost, Karren Poutanen, Susan Taylor, Maureen Yip, Lily Zhong, Xi Zoe McGeer, Allison J Mubareka, Samira |
author_sort | Jamal, Alainna J |
collection | PubMed |
description | We enrolled 91 consecutive inpatients with COVID-19 at 6 hospitals in Toronto, Canada, and tested 1 nasopharyngeal swab/saliva sample pair from each patient using real-time RT-PCR for severe acute respiratory syndrome coronavirus 2. Sensitivity was 89% for nasopharyngeal swabs and 72% for saliva (P = .02). Difference in sensitivity was greatest for sample pairs collected later in illness. |
format | Online Article Text |
id | pubmed-7337630 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-73376302020-07-08 Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2 Jamal, Alainna J Mozafarihashjin, Mohammad Coomes, Eric Powis, Jeff Li, Angel X Paterson, Aimee Anceva-Sami, Sofia Barati, Shiva Crowl, Gloria Faheem, Amna Farooqi, Lubna Khan, Saman Prost, Karren Poutanen, Susan Taylor, Maureen Yip, Lily Zhong, Xi Zoe McGeer, Allison J Mubareka, Samira Clin Infect Dis Brief Reports We enrolled 91 consecutive inpatients with COVID-19 at 6 hospitals in Toronto, Canada, and tested 1 nasopharyngeal swab/saliva sample pair from each patient using real-time RT-PCR for severe acute respiratory syndrome coronavirus 2. Sensitivity was 89% for nasopharyngeal swabs and 72% for saliva (P = .02). Difference in sensitivity was greatest for sample pairs collected later in illness. Oxford University Press 2020-06-25 /pmc/articles/PMC7337630/ /pubmed/32584972 http://dx.doi.org/10.1093/cid/ciaa848 Text en © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com. https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) |
spellingShingle | Brief Reports Jamal, Alainna J Mozafarihashjin, Mohammad Coomes, Eric Powis, Jeff Li, Angel X Paterson, Aimee Anceva-Sami, Sofia Barati, Shiva Crowl, Gloria Faheem, Amna Farooqi, Lubna Khan, Saman Prost, Karren Poutanen, Susan Taylor, Maureen Yip, Lily Zhong, Xi Zoe McGeer, Allison J Mubareka, Samira Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2 |
title | Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2 |
title_full | Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2 |
title_fullStr | Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2 |
title_full_unstemmed | Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2 |
title_short | Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2 |
title_sort | sensitivity of nasopharyngeal swabs and saliva for the detection of severe acute respiratory syndrome coronavirus 2 |
topic | Brief Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337630/ https://www.ncbi.nlm.nih.gov/pubmed/32584972 http://dx.doi.org/10.1093/cid/ciaa848 |
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