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Prevalence of Coronavirus Disease 2019 Infection and Outcomes Among Symptomatic Healthcare Workers in Seattle, Washington

BACKGROUND: Healthcare workers (HCWs) who serve on the front lines of the coronavirus disease 2019 (COVID-19) pandemic have been at increased risk for infection due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in some settings. Healthcare-acquired infection has been reported in si...

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Autores principales: Mani, Nandita S, Budak, Jehan Z, Lan, Kristine F, Bryson-Cahn, Chloe, Zelikoff, Allison, Barker, Gwendolyn E C, Grant, Carolyn W, Hart, Kristi, Barbee, Carrie J, Sandoval, Marissa D, Dostal, Christine L, Corcorran, Maria, Ungerleider, Hal M, Gates, Jeff O, Olin, Svaya V, Bryan, Andrew, Hoffman, Noah G, Marquis, Sara R, Harvey, Michelle L, Nasenbeny, Keri, Mertens, Kathleen, Chew, Lisa D, Greninger, Alexander L, Jerome, Keith R, Pottinger, Paul S, Dellit, Timothy H, Liu, Catherine, Pergam, Steven A, Neme, Santiago, Lynch, John B, Kim, H Nina, Cohen, Seth A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337651/
https://www.ncbi.nlm.nih.gov/pubmed/32548613
http://dx.doi.org/10.1093/cid/ciaa761
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author Mani, Nandita S
Budak, Jehan Z
Lan, Kristine F
Bryson-Cahn, Chloe
Zelikoff, Allison
Barker, Gwendolyn E C
Grant, Carolyn W
Hart, Kristi
Barbee, Carrie J
Sandoval, Marissa D
Dostal, Christine L
Corcorran, Maria
Ungerleider, Hal M
Gates, Jeff O
Olin, Svaya V
Bryan, Andrew
Hoffman, Noah G
Marquis, Sara R
Harvey, Michelle L
Nasenbeny, Keri
Mertens, Kathleen
Chew, Lisa D
Greninger, Alexander L
Jerome, Keith R
Pottinger, Paul S
Dellit, Timothy H
Liu, Catherine
Pergam, Steven A
Neme, Santiago
Lynch, John B
Kim, H Nina
Cohen, Seth A
author_facet Mani, Nandita S
Budak, Jehan Z
Lan, Kristine F
Bryson-Cahn, Chloe
Zelikoff, Allison
Barker, Gwendolyn E C
Grant, Carolyn W
Hart, Kristi
Barbee, Carrie J
Sandoval, Marissa D
Dostal, Christine L
Corcorran, Maria
Ungerleider, Hal M
Gates, Jeff O
Olin, Svaya V
Bryan, Andrew
Hoffman, Noah G
Marquis, Sara R
Harvey, Michelle L
Nasenbeny, Keri
Mertens, Kathleen
Chew, Lisa D
Greninger, Alexander L
Jerome, Keith R
Pottinger, Paul S
Dellit, Timothy H
Liu, Catherine
Pergam, Steven A
Neme, Santiago
Lynch, John B
Kim, H Nina
Cohen, Seth A
author_sort Mani, Nandita S
collection PubMed
description BACKGROUND: Healthcare workers (HCWs) who serve on the front lines of the coronavirus disease 2019 (COVID-19) pandemic have been at increased risk for infection due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in some settings. Healthcare-acquired infection has been reported in similar epidemics, but there are limited data on the prevalence of COVID-19 among HCWs and their associated clinical outcomes in the United States. METHODS: We established 2 high-throughput employee testing centers in Seattle, Washington, with drive-through and walk-through options for symptomatic employees in the University of Washington Medicine system and its affiliated organizations. Using data from these testing centers, we report the prevalence of SARS-CoV-2 infection among symptomatic employees and describe the clinical characteristics and outcomes among employees with COVID-19. RESULTS: Between 12 March 2020 and 23 April 2020, 3477 symptomatic employees were tested for COVID-19 at 2 employee testing centers; 185 (5.3%) employees tested positive for COVID-19. The prevalence of SARS-CoV-2 was similar when comparing frontline HCWs (5.2%) with nonfrontline staff (5.5%). Among 174 positive employees reached for follow-up at least 14 days after diagnosis, 6 reported COVID-related hospitalization; all recovered. CONCLUSIONS: During the study period, we observed that the prevalence of positive SARS-CoV-2 tests among symptomatic HCWs was comparable to that of symptomatic nonfrontline staff. Reliable and rapid access to testing for employees is essential to preserve the health, safety, and availability of the healthcare workforce during this pandemic and to facilitate the rapid return of SARS-CoV-2–negative employees to work.
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spelling pubmed-73376512020-07-08 Prevalence of Coronavirus Disease 2019 Infection and Outcomes Among Symptomatic Healthcare Workers in Seattle, Washington Mani, Nandita S Budak, Jehan Z Lan, Kristine F Bryson-Cahn, Chloe Zelikoff, Allison Barker, Gwendolyn E C Grant, Carolyn W Hart, Kristi Barbee, Carrie J Sandoval, Marissa D Dostal, Christine L Corcorran, Maria Ungerleider, Hal M Gates, Jeff O Olin, Svaya V Bryan, Andrew Hoffman, Noah G Marquis, Sara R Harvey, Michelle L Nasenbeny, Keri Mertens, Kathleen Chew, Lisa D Greninger, Alexander L Jerome, Keith R Pottinger, Paul S Dellit, Timothy H Liu, Catherine Pergam, Steven A Neme, Santiago Lynch, John B Kim, H Nina Cohen, Seth A Clin Infect Dis Major Articles and Commentaries BACKGROUND: Healthcare workers (HCWs) who serve on the front lines of the coronavirus disease 2019 (COVID-19) pandemic have been at increased risk for infection due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in some settings. Healthcare-acquired infection has been reported in similar epidemics, but there are limited data on the prevalence of COVID-19 among HCWs and their associated clinical outcomes in the United States. METHODS: We established 2 high-throughput employee testing centers in Seattle, Washington, with drive-through and walk-through options for symptomatic employees in the University of Washington Medicine system and its affiliated organizations. Using data from these testing centers, we report the prevalence of SARS-CoV-2 infection among symptomatic employees and describe the clinical characteristics and outcomes among employees with COVID-19. RESULTS: Between 12 March 2020 and 23 April 2020, 3477 symptomatic employees were tested for COVID-19 at 2 employee testing centers; 185 (5.3%) employees tested positive for COVID-19. The prevalence of SARS-CoV-2 was similar when comparing frontline HCWs (5.2%) with nonfrontline staff (5.5%). Among 174 positive employees reached for follow-up at least 14 days after diagnosis, 6 reported COVID-related hospitalization; all recovered. CONCLUSIONS: During the study period, we observed that the prevalence of positive SARS-CoV-2 tests among symptomatic HCWs was comparable to that of symptomatic nonfrontline staff. Reliable and rapid access to testing for employees is essential to preserve the health, safety, and availability of the healthcare workforce during this pandemic and to facilitate the rapid return of SARS-CoV-2–negative employees to work. Oxford University Press 2020-06-16 /pmc/articles/PMC7337651/ /pubmed/32548613 http://dx.doi.org/10.1093/cid/ciaa761 Text en © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com. https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)
spellingShingle Major Articles and Commentaries
Mani, Nandita S
Budak, Jehan Z
Lan, Kristine F
Bryson-Cahn, Chloe
Zelikoff, Allison
Barker, Gwendolyn E C
Grant, Carolyn W
Hart, Kristi
Barbee, Carrie J
Sandoval, Marissa D
Dostal, Christine L
Corcorran, Maria
Ungerleider, Hal M
Gates, Jeff O
Olin, Svaya V
Bryan, Andrew
Hoffman, Noah G
Marquis, Sara R
Harvey, Michelle L
Nasenbeny, Keri
Mertens, Kathleen
Chew, Lisa D
Greninger, Alexander L
Jerome, Keith R
Pottinger, Paul S
Dellit, Timothy H
Liu, Catherine
Pergam, Steven A
Neme, Santiago
Lynch, John B
Kim, H Nina
Cohen, Seth A
Prevalence of Coronavirus Disease 2019 Infection and Outcomes Among Symptomatic Healthcare Workers in Seattle, Washington
title Prevalence of Coronavirus Disease 2019 Infection and Outcomes Among Symptomatic Healthcare Workers in Seattle, Washington
title_full Prevalence of Coronavirus Disease 2019 Infection and Outcomes Among Symptomatic Healthcare Workers in Seattle, Washington
title_fullStr Prevalence of Coronavirus Disease 2019 Infection and Outcomes Among Symptomatic Healthcare Workers in Seattle, Washington
title_full_unstemmed Prevalence of Coronavirus Disease 2019 Infection and Outcomes Among Symptomatic Healthcare Workers in Seattle, Washington
title_short Prevalence of Coronavirus Disease 2019 Infection and Outcomes Among Symptomatic Healthcare Workers in Seattle, Washington
title_sort prevalence of coronavirus disease 2019 infection and outcomes among symptomatic healthcare workers in seattle, washington
topic Major Articles and Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337651/
https://www.ncbi.nlm.nih.gov/pubmed/32548613
http://dx.doi.org/10.1093/cid/ciaa761
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