Restriction endonucleases that cleave RNA/DNA heteroduplexes bind dsDNA in A-like conformation

Restriction endonucleases naturally target DNA duplexes. Systematic screening has identified a small minority of these enzymes that can also cleave RNA/DNA heteroduplexes and that may therefore be useful as tools for RNA biochemistry. We have chosen AvaII (G↓GWCC, where W stands for A or T) as a rep...

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Detalles Bibliográficos
Autores principales: Kisiala, Marlena, Kowalska, Monika, Pastor, Michal, Korza, Henryk J, Czapinska, Honorata, Bochtler, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337904/
https://www.ncbi.nlm.nih.gov/pubmed/32459314
http://dx.doi.org/10.1093/nar/gkaa403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337904/
https://www.ncbi.nlm.nih.gov/pubmed/32459314
http://dx.doi.org/10.1093/nar/gkaa403

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