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Restriction endonucleases that cleave RNA/DNA heteroduplexes bind dsDNA in A-like conformation
Restriction endonucleases naturally target DNA duplexes. Systematic screening has identified a small minority of these enzymes that can also cleave RNA/DNA heteroduplexes and that may therefore be useful as tools for RNA biochemistry. We have chosen AvaII (G↓GWCC, where W stands for A or T) as a rep...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337904/ https://www.ncbi.nlm.nih.gov/pubmed/32459314 http://dx.doi.org/10.1093/nar/gkaa403 |