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Nitrosative stress inhibits aminoacylation and editing activities of mitochondrial threonyl-tRNA synthetase by S-nitrosation
Structure and/or function of proteins are frequently affected by oxidative/nitrosative stress via posttranslational modifications. Aminoacyl-tRNA synthetases (aaRSs) constitute a class of ubiquitously expressed enzymes that control cellular protein homeostasis. Here, we found the activity of human m...
Autores principales: | Zheng, Wen-Qiang, Zhang, Yuying, Yao, Qin, Chen, Yuzhe, Qiao, Xinhua, Wang, En-Duo, Chen, Chang, Zhou, Xiao-Long |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337905/ https://www.ncbi.nlm.nih.gov/pubmed/32484546 http://dx.doi.org/10.1093/nar/gkaa471 |
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