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Nitrosative stress inhibits aminoacylation and editing activities of mitochondrial threonyl-tRNA synthetase by S-nitrosation

Structure and/or function of proteins are frequently affected by oxidative/nitrosative stress via posttranslational modifications. Aminoacyl-tRNA synthetases (aaRSs) constitute a class of ubiquitously expressed enzymes that control cellular protein homeostasis. Here, we found the activity of human m...

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Detalles Bibliográficos
Autores principales: Zheng, Wen-Qiang, Zhang, Yuying, Yao, Qin, Chen, Yuzhe, Qiao, Xinhua, Wang, En-Duo, Chen, Chang, Zhou, Xiao-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337905/
https://www.ncbi.nlm.nih.gov/pubmed/32484546
http://dx.doi.org/10.1093/nar/gkaa471

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