Macrophage development and activation involve coordinated intron retention in key inflammatory regulators

Monocytes and macrophages are essential components of the innate immune system. Herein, we report that intron retention (IR) plays an important role in the development and function of these cells. Using Illumina mRNA sequencing, Nanopore direct cDNA sequencing and proteomics analysis, we identify IR...

Descripción completa

Detalles Bibliográficos
Autores principales: Green, Immanuel D, Pinello, Natalia, Song, Renhua, Lee, Quintin, Halstead, James M, Kwok, Chau-To, Wong, Alex C H, Nair, Shalima S, Clark, Susan J, Roediger, Ben, Schmitz, Ulf, Larance, Mark, Hayashi, Rippei, Rasko, John E J, Wong, Justin J-L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Data Resources and Analyses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7337907/
https://www.ncbi.nlm.nih.gov/pubmed/32449925
http://dx.doi.org/10.1093/nar/gkaa435

Ejemplares similares

Ejemplares similares