PAICS contributes to gastric carcinogenesis and participates in DNA damage response by interacting with histone deacetylase 1/2

Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), an essential enzyme involved in de novo purine biosynthesis, is connected with formation of various tumors. However, the specific biological roles and related mechanisms of PAICS in gastric...

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Detalles Bibliográficos
Autores principales: Huang, Nan, Xu, Chang, Deng, Liang, Li, Xue, Bian, Zhixuan, Zhang, Yue, Long, Shuping, Chen, Yan, Zhen, Ni, Li, Guohui, Sun, Fenyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338359/
https://www.ncbi.nlm.nih.gov/pubmed/32632107
http://dx.doi.org/10.1038/s41419-020-2708-5

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