HB-EGF Activates the EGFR/HIF-1α Pathway to Induce Proliferation of Arsenic-Transformed Cells and Tumor Growth

Arsenic was recently identified as a pollutant that is a major cause of lung cancer. Since heparin-binding EGF-like growth factor (HB-EGF) was reported to be a promising therapeutic target for lung cancer, we investigated the role and mechanism of HB-EGF during arsenic-induced carcinogenesis and dev...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Lu, Yi-Fan, Wang, Chao-Shan, Xie, Yun-Xia, Zhao, Yan-Qiu, Qian, Ying-Chen, Liu, Wei-Tao, Wang, Min, Jiang, Bing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338480/
https://www.ncbi.nlm.nih.gov/pubmed/32695675
http://dx.doi.org/10.3389/fonc.2020.01019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338480/
https://www.ncbi.nlm.nih.gov/pubmed/32695675
http://dx.doi.org/10.3389/fonc.2020.01019

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