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Galectin-3 Released by Pancreatic Ductal Adenocarcinoma Suppresses γδ T Cell Proliferation but Not Their Cytotoxicity

Pancreatic ductal adenocarcinoma (PDAC) is characterized by an immunosuppressive tumor microenvironment with a dense desmoplastic stroma. The expression of β-galactoside-binding protein galectin-3 is regarded as an intrinsic tumor escape mechanism for inhibition of tumor-infiltrating T cell function...

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Detalles Bibliográficos
Autores principales:	Gonnermann, Daniel, Oberg, Hans-Heinrich, Lettau, Marcus, Peipp, Matthias, Bauerschlag, Dirk, Sebens, Susanne, Kabelitz, Dieter, Wesch, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338555/ https://www.ncbi.nlm.nih.gov/pubmed/32695112 http://dx.doi.org/10.3389/fimmu.2020.01328

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