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Effects of an APOE Promoter Polymorphism on Fronto-Parietal Functional Connectivity During Nondemented Aging
Background: The rs405509 polymorphism ofthe apolipoprotein E (APOE) promoter is related to Alzheimer’sdisease (AD). The T/T allele of rs405509 is known to decrease the transcription of the APOE gene and lead to impairments in specific brain structural networks with aging; thus, it is an important ri...
Autores principales: | Zhang, Qirui, Wu, Lingli, Du, Chao, Xu, Kai, Sun, Jinping, Zhang, Junying, Li, He, Li, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338603/ https://www.ncbi.nlm.nih.gov/pubmed/32694990 http://dx.doi.org/10.3389/fnagi.2020.00183 |
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