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Delicate Balances in Cancer Chemotherapy: Modeling Immune Recruitment and Emergence of Systemic Drug Resistance

Metronomic chemotherapy can drastically enhance immunogenic tumor cell death. However, the mechanisms responsible are still incompletely understood. Here, we develop a mathematical model to elucidate the underlying complex interactions between tumor growth, immune system activation, and therapy-medi...

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Detalles Bibliográficos
Autores principales: Tran, Anh Phong, Ali Al-Radhawi, M., Kareva, Irina, Wu, Junjie, Waxman, David J., Sontag, Eduardo D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338613/
https://www.ncbi.nlm.nih.gov/pubmed/32695118
http://dx.doi.org/10.3389/fimmu.2020.01376