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Delicate Balances in Cancer Chemotherapy: Modeling Immune Recruitment and Emergence of Systemic Drug Resistance
Metronomic chemotherapy can drastically enhance immunogenic tumor cell death. However, the mechanisms responsible are still incompletely understood. Here, we develop a mathematical model to elucidate the underlying complex interactions between tumor growth, immune system activation, and therapy-medi...
Autores principales: | Tran, Anh Phong, Ali Al-Radhawi, M., Kareva, Irina, Wu, Junjie, Waxman, David J., Sontag, Eduardo D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338613/ https://www.ncbi.nlm.nih.gov/pubmed/32695118 http://dx.doi.org/10.3389/fimmu.2020.01376 |
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